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Partial Wave Spectroscopic Detection of Colon Cancer Risk

Partial Wave Spectroscopic Detection of Colon Cancer Risk

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01095432
Acronym
Brushings
Enrollment
40
Registered
2010-03-30
Start date
2010-03-31
Completion date
2015-11-30
Last updated
2016-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon Cancer, Ulcerative Colitis

Keywords

Colonoscopy, Flexible Sigmoidoscopy

Brief summary

The purpose of this study is to study samples of rectal mucosa (the moist lining of the rectum) using a new light scattering technology, called partial wave spectroscopy (PWS) in patients who will undergo a standard of care colonoscopy or a flexible sigmoidoscopy and have a history of ulcerative colitis (UC).

Detailed description

The purpose of this study is to study samples of rectal mucosa (the moist lining of the rectum) using a new light scattering technology, called partial wave spectroscopy (PWS)in patients who will undergo a colonoscopy or a flexible sigmoidoscopy and have a history of ulcerative colitis (UC). PWS has been recently developed to allow scientists to learn about any changes to the cells that may indicate a risk of developing colon cancer. We believe that the PWS test will more accurately detect the risk of colon cancer.

Interventions

PROCEDUREPWS Testing

Partial wave spectroscopy (PWS)has been developed to allow scientists to learn about any changes to the cells that may indicate a risk of developing colon cancer.

Sponsors

Northwestern University
CollaboratorOTHER
University of Chicago
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patient must be 18 years old or older. * Patient is already scheduled for a standard of care colonoscopy or flexible sigmoidoscopy. * Patient has not received chemotherapy. * History of ulcerative colitis.

Exclusion criteria

* Patient is unable to give informed consent.. * Patient has received chemo or radiation therapy within the past 3 months.

Design outcomes

Primary

MeasureTime frameDescription
Study samples of rectal mucosa (the moist lining of the rectum) using PWS.1 yearSamples will be collected and then shipped to Northwestern University for analysis using PWS. This is to assess accuracy of detecting the risk for colon cancer.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026