Crohn's Disease(CD), Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome, Ulcerative Colitis
Conditions
Keywords
HRV, emotion, cognition, stress, cortisol, Autonomic nervous system
Brief summary
The study aims at showing that the susceptibility in the stress is more raised at the person affected digestive pathologies (SII or IBD) in forgiveness than healthy subjects.
Detailed description
The objective of the study which we wish to lead consists in looking for, at the patients SII and IBD in forgiveness, the existence of a correlation between the rate of cortisol(Hormone of the stress) and the level of HRV (Heart Rate Variability) to estimate the inhibitive fronto-amygdalien tonus. So we make the hypothesis that the persons affected by digestive pathologies of type SII or IBD would present an emotional and physiological vulnerability more important than unhurt subjects of pathologies.
Interventions
BEHAVIORALemotion
Show that the susceptibility in the stress (recording of Heart Rate Variability;viewing films;...) is more important at the person affected by digestive pathologies (SII or IBD) in forgiveness than to unhurt subjects of pathologies.
Sponsors
French National Society of Gastroenterology
Association François Aupetit
University Hospital, Grenoble
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients with SII :Membership to the Social Security,SII defined according to the criteria Rome III. * Patients with IBD :Membership to the Social Security,patients with a ulcerative colitis(UC) or a Crohn's disease (CD)ileal and/or colic.
Exclusion criteria
* Existence of a severe affectation on the general plan (cardiac,respiratory,hematological,renal,hepatic,cancerous), * Subject diabetic, * Pregnant or breast-feeding woman, * Subject included in another clinical and\\or therapeutic trial or having been included in a clinical and\\or therapeutic trial for less than a month, * Subject presenting a psychiatric pathology evident, * Person under guardianship.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RATE PLASMATIQUE OF CORTISOL COUPLED WITH THE CARDIAC VARIABILITY | 24 MONTHS |
Secondary
| Measure | Time frame |
|---|---|
| SCORES OF DEPRESSIVE SYMPTOMATOLOGIE AND ANXIETY, RATE PLASMATIQUES OF CATECHOLAMINES, LEPTINE, ADIPONECTINE AND PRO-INFLAMMATORY CYTOKINES. | 24 MONTHS |
Countries
France
Outcome results
None listed