Proteinuria
Conditions
Keywords
focal segmental glomerulosclerosis
Brief summary
Patients with focal segmental glomerulosclerosis (FSGS) who progress rapidly to end stage renal disease (ESRD) are at highest risk for development of recurrence of proteinuria following kidney transplantation. This study will look at serum specimens pre and post transplant, as well as kidney transplant specimens pre and post reperfusion to identify where the defects has occured that results in recurrence of proteinuria in a given kidney transplant.
Detailed description
This study will retrospectively review patient's medical records for protein in the urine, blood creatinine and kidney biopsy results. Also character of the fluid used to flush the kidney before transplant will be analyzed.
Interventions
None listed
Sponsors
University of Miami
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 25 Years
Healthy volunteers
No
Inclusion criteria
* Kidney transplant recipients * Pediatric males and females up to the age of 25 years old.
Exclusion criteria
* Transplant recipients other than kidney
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Explain mechanisms behind the development of proteinuria in patients immediately after receiving a kidney transplant | through study completion, an average of 5 years | chart review |
Countries
United States
Contacts
Primary ContactGeorge Burke, M.D.
Backup ContactLissett Moni
Outcome results
None listed