Effect of Nocturnal Administration of Anti-hypertensive Medications in NoN-dippers

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01091753

Enrollment

Registered

2010-03-24

Start date

2008-03-31

Completion date

2009-09-30

Last updated

2010-10-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Keywords

Non-dipper HTN patient

Brief summary

The purpose of this study is to determine the effect of nocturnal administration of Anti-hypertensive medications in Non-dippers. Efficacy variables. 1. ECHO 2. 24hr. horter 3. IMT 4. BUN/crea, urine analysis (microalbulinuria 5. Cardio vascular event.

Interventions

DRUGValsaltan, amlodipine

nti hypertensive medication time (nocturnal administration vs morning administration

Study design

Allocation

RANDOMIZED

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

1. Essential hypertension (stage 1-2) 2. 24hr. holer : non-dipper 3. Age 18 \ 70.

Exclusion criteria

1. Any known malignant disease 2. Renal failure , creatinine \>2.0mg/dl 3. Liver disease

Design outcomes

Primary

Measure	Time frame
IMT(intima media thickness) Measure data(Sono)	baseline

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026