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Autologous Serum Skin Test and Serum IL-18 Levels in Chronic Idiopathic Urticaria and Respiratory Allergic Diseases

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01091402
Enrollment
Unknown
Registered
2010-03-24
Start date
2009-01-31
Completion date
Unknown
Last updated
2010-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Allergic Diseases, Urticaria

Keywords

autologous serum skin test, IL-18

Brief summary

One of the proposed mechanisms in CU is autoimmunity. It was shown by a positive response to autologous serum skin test (ASST)in almost half of chronic urticaria (CU) patients. IL-18 also play a role in autoimmune disorders. The investigators aim was to investigate the relationship of ASST and IL-18 in CU and respiratory allergic diseases.

Interventions

PROCEDUREautologous serum skin test, serum IL-18

Sponsors

Eskisehir Osmangazi University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* adult patients * chronic urticaria patients * stable asthma patients * allergic rhinitis patients with sensitized to pollens * normal controls without atopic and skin disease.

Exclusion criteria

* unwillingness to the study * other dermatological problems that could affect the skin test * use of antihistamine drugs

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026