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Improving Safety by Basic Computerizing Outpatient Prescribing

Improving Safety by Basic Computerizing Outpatient Prescribing

Status
Completed
Phases
Phase 2Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01091038
Enrollment
228
Registered
2010-03-23
Start date
2001-08-31
Completion date
2007-08-31
Last updated
2023-10-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adverse Drug Events

Keywords

Adverse drug events, medical errors, computerized physician order entry, clinical decision support

Brief summary

The study will measure the effect of basic clinical decision support on medical errors and adverse drug events in the ambulatory setting.

Interventions

OTHERBasic Clinical Decision Support

The computerized physician order entry (CPOE) intervention provides physicians with a menu of medications from the formulary, default doses, and a range of potential doses for each medication. Physicians were required to enter dosage, route, and frequency for all orders. Also, CPOE ensured that all orders were legible and included the prescribing physician's signature. For a number of medications, the system displayed relevant laboratory results on the screen at the time of ordering. Other features included consequent orders, which are orders that should follow from other orders, and drug-allergy checking, drug-drug interaction checking, and drug-laboratory checking. This included checking for the most frequent drug allergies, about 80 carefully selected drug-drug interactions, and several drug-laboratory combinations

OTHERRoutine Care

Routine Care

Sponsors

Brigham and Women's Hospital
CollaboratorOTHER
Indiana University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
TRIPLE (Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL

Inclusion criteria

* provider practicing at sites implementing order entry with basic clinical decision support using either the longitudinal medical record (LMR) or Medical Gopher

Exclusion criteria

* provider or practice unwilling to participate

Design outcomes

Primary

MeasureTime frameDescription
Adverse Drug Events6 monthsAdverse drug events are measured through use of a computerized surveillance system augmented by focused structured human review
Medical Errors6 monthsMedical Errors are identified through a computerized surveillance system with structured human review

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026