Correlation Between Vitamin D Status and Bone Mineral Density in Patients With Hemophilia

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01090206

Enrollment

Registered

2010-03-19

Start date

2010-03-31

Completion date

2015-03-31

Last updated

2016-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemophilia A, Hemophilia B, Vitamin D Deficiency

Keywords

Hemophilia, Vitamin D

Brief summary

Study will look at baseline Vitamin D levels, calcium, albumin, liver enzymes, testosterone, osteocalcin, urine N telopeptides, bone mineral density, nutritional assessment and physical activity assessment of boys with hemophilia A or B (ages 2-20 yrs). Patients with low vitamin D levels will receive therapeutic doses of Vitamin D. At end of one year follow up studies will be repeated.

Interventions

DIETARY_SUPPLEMENTVitamin D and calcium

Doses will be based on Vitamin D levels

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SCREENING

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

2 Years to 21 Years

Healthy volunteers

Inclusion criteria

* clinical diagnosis of Hemophilia A or B * ages 2-21 years

Exclusion criteria

* therapeutic vitamin D or calcium supplementation within 3 months of study entry

Design outcomes

Primary

Measure	Time frame
Correlate between Vitamin D deficiency, low bone mass and lack of weight bearing physical activity	1year

Secondary

Measure	Time frame
Determine bone mass (density) in hemophilia patients	1 yr
establish dose and duration of treatment with vitamin D	1 yr

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026