Metformin Versus Insulin in the Treatment of Gestational Diabetes Mellitus

Metformin Versus Insulin in the Treatment of Gestational Diabetes Mellitus: a Randomized Controlled Study

Status

Completed

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01087866

Enrollment

Registered

2010-03-16

Start date

2005-06-30

Completion date

2009-10-31

Last updated

2010-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational Diabetes Mellitus

Keywords

Gestational diabetes mellitus, treatment, metformin

Brief summary

The purpose of this study is to determine if metformin therapy prevents fetal macrosomy in gestational diabetes mellitus to the same extent as insulin therapy.

Interventions

DRUGMetformin

DRUGInsulin

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Inclusion criteria

* gestational diabetes mellitus diagnosed between 12-34 pregnancy weeks if normoglycemia is not reached with diet

Exclusion criteria

* hypertension with pharmacological treatment or preeclampsia * multiple pregnancy * liver or kidney disease

Design outcomes

Primary

Measure	Time frame
Percentage of fetal macrosomy	—

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 9, 2026