Skip to content

The Impact of Post-tetanic Count on Subsequent Train-of-four During Recovery From Rocuronium

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01086176
Enrollment
22
Registered
2010-03-12
Start date
2010-03-31
Completion date
2010-04-30
Last updated
2010-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-tetanic Count on One Arm, the Other Arm is the Control

Brief summary

The purpose of this study is to see how long does the effect of a post-tetanic facilitation last on subsequent train-of-four. The investigators hypothesis is that the effect last at least 30 minutes.

Interventions

DEVICENMT (a device that can do neurostimulation and can record the response on the stimulation by Datex)

on one side, we do a post-tetanic count, on the other side we don't, after, we do train-of-four on both sides and check the difference

Sponsors

Maisonneuve-Rosemont Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* Patient having general anesthesia in dorsal decubitus with both arm available for at least an hour and a half

Exclusion criteria

* Age \>75 or \<18 * Neuromuscular disease * difficult laryngoscopy predicted * Allergy to rocuronium * Malignant hyperthermia * Full stomach * Drugs the influence neuromuscular blockers * Decision of the clinician to exclude his patient

Design outcomes

Primary

MeasureTime frame
The difference at 30 minutes after the post-tetanic count between the TOF% in both arms, we expect a difference of more than 10%

Secondary

MeasureTime frame
The difference at 30 minutes after the post-tetanic count on the T1% (of the calibrated T1) in both arms, we expect a difference of more than 10%
The difference of the slope of recuperation on TOF and T1% after a post-tetanic count vs the control arm that had no tetanic stimulation

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026