Infection
Conditions
Keywords
Infection rate of VEPTR-Implants, VEPTR. Vertical Expandable, Prosthetic Titanium Rib
Brief summary
The study is conducted to analyse the infection rate in children treated with VEPTR-Implants for severe spine or thoracic deformities.
Detailed description
Spinal and thoracic deformities in children can be treated with vertical expandable prosthetic titanium ribs (VEPTR©, Synthes GmbH®) to stimulate thoracic and spinal growth. With these implants children's symptoms and conditions can be slowed, halted or even reversed. Because of the dynamic character of the deformity and the growth of the children, the implants have to be lengthened about every half a year. With each operation there is a small risk of infection, which might increase with number of previous surgeries. Implant associated infections are often not clinical apparent and only found in microbiological analysis. To objectify the infection rate, identify potential precursors of infections and the relevance of asymptomatic infections in children with these implants a prospective study is conducted.
Interventions
DEVICEMicrobiological analysis of retained VEPTR Implants
Implants have to be adapted every half a year, the retained implants during revision are analysed for biological colonization.
Sponsors
University Children's Hospital Basel
Centre Hospitalier Universitaire Vaudois
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Years to 30 Years
Healthy volunteers
No
Inclusion criteria
* all patients admitted at the University Children's Hospital Basel in whom a VEPTR©-implant or parts of it will be removed.
Exclusion criteria
* obvious contamination of an explanted component occurred in the operating room.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infection rate of VEPTR Implants | two years |
Countries
Switzerland
Contacts
Primary ContactChristian Plaass, MD
Backup ContactCarol Claudius Hasler, MD, PhD
Outcome results
None listed