Verruca Vulgaris
Conditions
Keywords
Warts, Verruca vulgaris, Liquid Nitrogen, Cantharidin, combination treatment
Brief summary
The purpose of the study was to see if liquid nitrogen, a commonly used treatment for warts, is more effective if it is used alone, or if it is more effective if combined with cantharidin, a topical treatment also commonly used for warts (verruca vulgaris).
Interventions
DRUGLiquid nitrogen and cantharidin
Liquid nitrogen applied to wart(s), then cantharidin 1% topical applied afterward.
DRUGLiquid nitrogen and topical placebo
Liquid nitrogen applied to wart(s), then placebo vehicle applied thereafter.
Sponsors
North Idaho Dermatology
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
1. common warts on non-genital, non-facial skin 2. otherwise healthy 3. between 18-65 and able to give informed consent 4. capable of tolerating treatment
Exclusion criteria
1. Ill-health 2. Poor tolerance or sensitivity to treatments in study 3. \<18 years old; \>65 years old 4. verruca plana or condyloma acuminata 5. immunosuppression or immune dysfunction 6. significant peripheral vascular disease 7. significant sensitivity to cold 8. epidermodysplasia verruciformis 9. mosaiform warts or periungual warts
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of common warts cleared | 12 weeks | Percentage of treated warts cleared with treatment, as measured with dermatoscopic examination, after 12 weeks. |
Countries
United States
Outcome results
None listed