Airway Complications
Conditions
Keywords
end tidal concentration
Brief summary
The purpose of this study is to determine the optimal volatile anaesthetic (sevoflurane and desflurane) to remove a Supreme LMA in adults in which there is minimal airway response. Null hypothesis: there is no significant difference between the optimal end tidal concentration of sevoflurane and desflurane for Supreme LMA removal.
Detailed description
The manufactures' instructions for removal of the LMA recommend waiting until protective reflexes have returned. However, the appropriate timing for removal remains controversial. A more frequent incidence of airway hyperreactivity and complications has been reported by some studies when the LMA was removed in the awake state versus the anesthetized state. Techniques that reduce the time from LMA removal to the return of protective airway reflexes would minimize the risk of aspiration, contamination, or airway obstruction. With increasingly common use of Supreme LMA in anaesthetic practice, a safe and suitable depth for removal of the Supreme LMA requires research. Thus the determination of the optimal end-tidal concentration of commonly used volatile agents ie. Sevoflurane and Desflurane for Supreme LMA removal requires research, both for patient safety and minimising anaesthetic costs in dealing with airway complications.
Interventions
Comparing the optimal end-tidal concentration sevoflurane and desflurane for LMA extubation
Comparing the optimal end-tidal concentration sevoflurane and desflurane for LMA extubation
Sponsors
Study design
Eligibility
Inclusion criteria
1. ASA 1-2 patients 2. Age 18 - 49 years old 3. Elective surgery of short duration ( \< 2 hours ) which require local anaesthetic infiltration
Exclusion criteria
1. Upper respiratory tract symptoms in the previous 10 days 2. Risk of gastric oesophageal reflux or regurgitation 3. Known or predicted difficult airway 4. Poor dentition with high risk of damage 5. BMI \> 30 kg/m2 6. Refusing to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Optimal end tidal concentration of sevoflurane/ desflurane | 6 months |
Secondary
| Measure | Time frame |
|---|---|
| presence of airway response | 10 mins after surgery |
Countries
Malaysia