Vitiligo
Conditions
Keywords
vitiligo
Brief summary
We will investigate the process of vitiligo induction and the influence of different commonly used cream treatments on this process. Studies comparing different treatments for vitiligo in the induction stage of the disease are still missing. The study hypothesis = cream treatment can stop actively spreading vitiligo lesions during the early induction stage of the disease.
Interventions
DRUGtopical tacrolimus treatment
4 applications (day 1,day 3, day 6 and day10)
DRUGtopical pimecrolimus treatment
4 applications (day 1, day 3, day 6 and day 10)
DRUGlocal mometasone furoate treatment
4 applications (day 1, day 3, day 6 and day 10)
DRUGcold cream
4 applications (day 1, day 3, day 6 and day 10)
Sponsors
University Hospital, Ghent
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Male and female, * Age 18-70 years, * Extensive vitiligo (\> 50% body surface area), * Patients asking for depigmenting therapy, * Not pregnant.
Exclusion criteria
* Children, * Non extensive vitiligo (\< 50% boy surface area), * Patients not asking for depigmenting therapies, * Pregnant.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| percentage of skin pigmentation in the treated area | after 1 day, 10 days, 30 days and 60 days | digital image analysis system for surface measurement |
Countries
Belgium
Outcome results
None listed