Skip to content

Stiffness of the Skin and Joints in Relation to Carpal Tunnel Syndrome

Correlation of Joint Stiffness and Stiffness of the Skin and the Prevelation of Carpal Tunnel Syndrome (CTS)

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01081860
Acronym
STIF-CTS
Enrollment
40
Registered
2010-03-05
Start date
2010-05-31
Completion date
2010-12-31
Last updated
2010-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal Tunnel Syndrome

Keywords

Carpal tunnel syndrome, CTS, Skinstiffness, Jointstiffness

Brief summary

The exact etiology of CTS remains yet unknown. A rise in carpal tunnel pressure is well documented, but why this phenomenon occurs is yet unknown in most patients. There is an absolute or relative narrowing of the carpal tunnel, which results in a compression of the median nerve. The investigators postulate, that a stiffer flexor retinaculum (roof of carpal tunnel) will be less compliant. As a consequence of this stiffer retinaculum the pressure in the carpal tunnel will rise more quickly in stiff patients resulting in CTS-complaints. A relation between connective tissue composition and joint stiffness is proven. This relationship possibly extends to a relation between stiffness of the skin, joint stiffness and the prevalence of CTS.

Interventions

None listed

Sponsors

St. Antonius Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Caucasian * Carpal tunnel release OR Trigger finger OR Dupuytren OR an acute trauma to the hand

Exclusion criteria

* Hypo-/hyperthyroidism * Diabetes * Arthritis * Pregnancy * Obesity (BMI \>30) * Anatomical anomalies

Design outcomes

Primary

MeasureTime frameDescription
Joint stiffnessIn the 1st monthThe active range of motion (elbow, wrist, knee and ankle) is measured with a standard goniometer.
Stiffness of the skinin the 1st monthSkinstiffness is measured with a suction cup

Secondary

MeasureTime frameDescription
Physical activitiesIn the 1st monthBoston Questionairre

Countries

Netherlands

Contacts

Primary ContactBo Verwer
b.verwer@antoniusziekenhuis.nl

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026