0.05 mg Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy

0.05 vs. 0.1 Milligram Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy With/Without Anterior and Posterior Vaginoplasty

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01080911

Enrollment

Registered

2010-03-04

Start date

2010-03-31

Completion date

2012-12-31

Last updated

2011-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Keywords

Spinal morphine, Vaginal hysterectomy

Brief summary

This study aims to compare the effect of spinal morphine between the dose 0.05 mg and 0.1 mg on the amount of morphine during the first 24 hours postoperative.

Interventions

DRUGMorphine

spinal morphine 0.05 mg

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Female ASA 1-3 * Undergoing vaginal hysterectomy with/without anterior and posterior vaginoplasty * Can operate PCA device

Exclusion criteria

* History of allergy to the study drugs * History of bleeding tendency * History of infection at the back * Patient refuse to have spinal anesthesia * History of CAD or CVD

Design outcomes

Primary

Measure	Time frame
the amount of 24 hours morphine	24 hour

Countries

Thailand

Contacts

Primary ContactSirilak Suksompong, MD

sisuk@mahidol.ac.th6624113256

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026