The Identification and Characterization of Autonomic Dysfunction in Migraineurs With and Without Auras

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01080287

Enrollment

Registered

2010-03-04

Start date

2009-09-30

Completion date

2011-09-30

Last updated

2012-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine

Keywords

autonomic, orthostatic, syncope, biopsy, prevalence of autonomic dysfunction in migraineurs with orthostatic intolerance, characterize autonomic findings utilizing neurocardiac testing, neurophysiological testing and skin biopsies to analyze autonomic fibers in the dermis

Brief summary

This is a study to compare subject response and symptoms resulting from administration of three clinical assessments. \* The 3 assessments are 1. passive upright tilt table testing, 2. quantitative sudomotor axon reflex testing (QSART)and 3. punch biopsy. The comparison of results will be from two subject groups: * Group A, the migraine suffering patient with or without aura * Group B, the migraine suffering patient with or without aura who has diagnosed orthostatic intolerance (i.e.,feeling dizzy or faint when making a body position change).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* age 18 to 65 * male or female * migraine diagnosis * may or may not have orthostatic intolerance * able to demonstrate study understanding and complete informed consent process

Exclusion criteria

* subjects who do not meet inclusion criteria * subjects unable to complete informed consent process

Countries

United States

Outcome results