0.05 Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy

The Comparison of 0.05 vs. 0.1 Milligram Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy With/Without Anterior and Posterior Vaginoplasty

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01079754

Enrollment

Registered

2010-03-03

Start date

2010-03-31

Completion date

2011-12-31

Last updated

2011-09-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Vaginal Hysterectomy

Keywords

Spinal morphine 0.05 mg, Spinal morphine

Brief summary

This study aims to compare the efficacy of 0.05 mg and 0.1 mg spinal morphine in reducing postoperative morphine requirement in patients undergoing vaginal hysterectomy with/without anterior and posterior vaginoplasty.

Interventions

DRUGSpinal morphine 0.05 mg

Patient received spinal morphine 0.05 mg

DRUGSpinal morphine 0.1 mg

Patient received spinal morphine 0.1 mg

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Female ASA physical status 1-3 * Undergoing vaginal hysterectomy with/without anterior and posterior vaginoplasty * Be able to operate patient-controlled analgesia (PCA)

Exclusion criteria

* Allergy to the study drugs * History of bleeding tendency * Infection at the back * Refuse to spinal anesthesia * History of CAD or CVA

Design outcomes

Primary

Measure	Time frame
The total amount of morphine that the patient required during the first 24-h postoperative.	24 hours

Countries

Thailand

Contacts

Primary ContactSirilak Suksompong, MD

sisuk@mahidol.ac.th6624113256

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026