Rehabilitation, Spinal Cord Injury, Urinary Tract Infection
Conditions
Keywords
urinary tract infection, prevention, rehabilitation, spinal cord injury
Brief summary
The purpose of this study is to establish whether cranberry capsules reduce rates of urinary tract infections during initial rehabilitation immediately after spinal cord injury.
Interventions
DIETARY_SUPPLEMENTCranberry capsules
Cranberry capsules, 550mg, or placebo capsules, two capsules three times daily during in-patient rehabilitation
Sponsors
Uppsala University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Previously essentially healthy 2. Newly acquired spinal cord injury, T12 level or higher 3. Receiving in-patient care on the rehabilitation ward. 4. Expected admission duration \>= 4 weeks 5. 16 years old or older
Exclusion criteria
1. Current or previous disorder that increases the risk of urinary tract infection including diabetes, urological disorder, previous operation on urinary tracts or kidneys, immune dysfunction 2. Severe head injury with impairment of cognitive function 3. Allergy to cranberry 4. Renal failure 5. Warfarin (Coumarin) treatment with unstable INR 6. Current symptomatic urinary tract infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of symptomatic urinary tract infections per patient per month during in-patient post acute rehabilitation | At end of study |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of in-patient rehabilitation days on which patients were unable to participate in active rehabilitation due to urinary tract infection. | At end of Study |
| Patient's experience of urinary symptoms in the absence of symptomatic urinary tract infection. | At end of study |
Countries
Sweden
Outcome results
None listed