Cholecystectomy
Conditions
Keywords
transvaginal access for cholecystectomy
Brief summary
Transvaginal hybrid procedures are of interest as an available NOTES procedure for the clinical routine. The gynaecologists' experiences and the available studies report on low morbidity related to the transvaginal access. However, little is known about the vaginal and intraabdominal microbial contamination due to the transvaginal approach. The aim of this cohort study is to evaluate the microbial colonisation and contamination in patients with transvaginal hybrid and conventional laparoscopic cholecystectomy. Therefore, pre- and intraoperative microbiological evaluations will be performed in patients with transvaginal hybrid cholecystectomy and laparoscopic cholecystectomy.
Interventions
PROCEDURESmear test vaginally, intraabdominally
Pre- and intraoperative smear tests of the vagina and douglas are performed.
Sponsors
Cantonal Hospital of St. Gallen
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* indication for elective cholecystectomy * informed consent for laparoscopic cholecystectomy or transvaginal hybrid cholecystectomy
Exclusion criteria
* cholecystitis * intraabdominal infection * existing antibiotic therapy * adnexitis * pelvic inflammatory disease * infection (CRP \> 10 mg /l; Lc \> 11 G/l)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Microbial colonisation and contamination vaginally and intraabdominally | 1 day |
Secondary
| Measure | Time frame |
|---|---|
| Morbidity (wound, vaginal and intraabdominal infection) two weeks and six weeks postoperatively | 6 weeks |
Countries
Switzerland
Outcome results
None listed