Physical Exercise Versus Cognitive-behavioral Therapy (CBT) for Panic Disorders: A Randomised Controlled Trial

Effects of Physical Exercise on Anxiety and Co-morbid Emotional Disturbances: A Clinical Trail in a Day Care Unit

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01076777

Enrollment

Registered

2010-02-26

Start date

2007-05-31

Completion date

2009-12-31

Last updated

2010-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Panic Disorder

Keywords

Panic disorder, Physical exercise, Cognitive-behavioral therapy, Manualized

Brief summary

The purpose of this study is to compare manualised physical exercise conducted in groups to manualised cognitive-behavioral therapy conducted in groups as treatment for panic disorder with or without agoraphobia.

Interventions

BEHAVIORALPhysical exercise

Manualised Exercise performed in groups (5-8 participants per group). 3 sessions (á 60 minutes) per week for 12 consecutive weeks

BEHAVIORALCognitive-behavioral therapy

Cognitive-behavioral therapy conducted in groups (5-8 participants per group). 1 session (á 2-2.25 hours depending on group size) per week for 12 consecutive weeks

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Written informed consent obtained * Clinical diagnosis of panic disorder with and without agoraphobia according to The Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR, 4th ed., text revision; American Psychiatric Association, 2000), established through administration of Structural Clinical Interview for DSM-IV axis I disorders (SCID I; First, Spitzer, Gibbon, & Williams, 1995).

Exclusion criteria

* Brain-organic disorders according to DSM-IV-TR * The presence of psychotic disorders according to DSM-IV-TR, established through administration of SCID I * Present substance-abuse * Medical condition that excludes participation in physical activity * Major Depressive Disorder according to DSM-IV-TR established through administration of SCID I.

Design outcomes

Primary

Measure	Time frame
Panic distress/disability - Self-report & Clinician-rating	Baseline; Pre-treatment; Post-treatment; 6-months follow-up; 12-monthts follow-up
Mobility Inventory (MI) - Alone & Accompanied	Baseline; Pre-treatment; Post-treatment; 6-months follow-up; 12-monthts follow-up
Agoraphobic Cognitions Questionnaire (ACQ)	Baseline; Pre-treatment; Post-treatment; 6-months follow-up; 12-monthts follow-up
Body Sensations Questionnaire	Baseline; Pre-treatment; Post-treatment; 6-months follow-up; 12-monthts follow-up
Panic frequency - Self-report & Clinician-rating	Baseline; Pre-treatment; Post-treatment; 6-months follow-up; 12-monthts follow-up

Secondary

Measure	Time frame
State-Trait Anxiety Inventory - State & Trait (STAI S/T)	Baseline; Pre-treatment; Post-treatment; 6-months follow-up; 12-monthts follow-up
Beck Depression Inventory II (BDI-II)	Baseline; Pre-treatment; Post-treatment; 6-months follow-up; 12-monthts follow-up
Quality of Life Inventory (QoLI)	Baseline; Pre-treatment; Post-treatment; 6-months follow-up; 12-monthts follow-up
Beck Anxiety Inventory (BAI)	Baseline; Pre-treatment; Post-treatment; 6-months follow-up; 12-monthts follow-up

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026