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Improving Gait in Multiple Sclerosis (MS) - Strength Training or Treadmill Walking?

Strength Training or Treadmill Walking? A Randomized Control Study on the Effect on Gait in Multiple Sclerosis

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01074827
Enrollment
28
Registered
2010-02-24
Start date
2010-03-31
Completion date
2011-04-30
Last updated
2015-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis

Keywords

Multiple Sclerosis, Walking ability, Strength, Balance, Treadmill walking

Brief summary

The objective of this study is to evaluate the effect of strength training for the lower extremities and treadmill training on walking ability in persons with Multiple Sclerosis. The study is a randomized control trial with two groups and the intervention is 8 weeks of intensive strength training or treadmill walking. Primary outcome measure is walking ability, secondary outcome measures are balance, work economy and strength.

Interventions

OTHERStrength training and treadmill training

Eight weeks of intensive strength training or treadmill training

Sponsors

Norwegian University of Science and Technology
CollaboratorOTHER
Helse Midt-Norge
CollaboratorOTHER
St. Olavs Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Diagnosed with Multiple Sclerosis,classified as relapsing remitting,or primary/secondary progressive * Expanded Disability Status Scale (EDSS)score of ≤ 6 * Reduced walking ability (subjectively experienced)

Exclusion criteria

* persons with a level of ataxia, clinically assessed, that would affect their ability to perform the training. * spasticity requiring stretching og treatment with baclofen. * Other, not MS-related, conditions affecting walking ability.

Design outcomes

Primary

MeasureTime frame
Walking ability8 weeks

Secondary

MeasureTime frame
Strength8 weeks
Work economy O28 weeks
Balance8 weeks

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026