Predictive Factors of Clinical, Laboratory and Imaging Findings Routinely Used in Diagnosing Thyroid Cancer

Defining Predictive Factors of Clinical, Laboratory and Imaging Criteria Routinely Used in the Diagnosis of Thyroid Cancer: Observational, Prospective Multicentered Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01074684

Acronym

TIR-2009-01

Enrollment

959

Registered

2010-02-24

Start date

2010-01-31

Completion date

2021-12-01

Last updated

2023-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Cancer

Keywords

diagnosis, nodules, fine needle aspiration

Brief summary

The purpose of this study is to describe the correlation between the cytohistology exam of patients undergoing thyroid surgery, and the predictive values of: suspicious clinical findings, preoperative thyroid imaging, and the incidence of thyroid cancer in cytologically negative nodes.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Consecutive patients presenting for thyroid disease (palpable nodules) * Indication for surgery * Age \> 18 years * Signed informed consent for surgery * Signed informed consent for data collection

Exclusion criteria

* Concurrent condition that contraindicates surgery * Clinical or radiologic evidence of locally advanced tumor * Clinical or radiologic evidence of metastatic lymph nodes or distant metastases * Nonpalpable nodes

Design outcomes

Primary

Measure	Time frame
positive predictive value of preoperative suspicious clinical, laboratory and imaging findings	at baseline

Countries

Italy

Outcome results