Semen Analysis After Proton Therapy for Prostate Cancer

Semen Analysis Following Definitive Treatment of Prostate Cancer With Proton Radiation Therapy Alone

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01072513

Acronym

PR08

Enrollment

Registered

2010-02-22

Start date

2010-03-31

Completion date

2015-07-31

Last updated

2016-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate Cancer

Keywords

Semen Analysis, Prostate Cancer, Proton Radiation

Brief summary

The purpose of this study is to evaluate semen for changes following treatment with proton radiation therapy.

Interventions

OTHERSemen analysis

Semen analysis before and after proton radiation therapy.

Study design

Allocation

Intervention model

SINGLE_GROUP

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

\- Diagnosis of low to intermediate risk prostate cancer and elected to have proton radiation therapy at University of Florida Proton Therapy Institute (UFPTI).

Exclusion criteria

* Current use of Flomax, Hytrin, Cardura, Uroxatral, or Rapaflo. * History of vasectomy. * Current use of Lupron, Zoladex, Trelstar, Casodex, Eulexin. * Current use of Avodart or Proscar.

Design outcomes

Primary

Measure	Time frame
Post treatment sperm count	12 months after radiation therapy

Secondary

Measure	Time frame	Description
Compare changes in sperm motility, sperm morphology and semen PH.	12 months after radiation therapy	This is composite measure

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026