Intraoperative Floppy Iris Syndrome
Conditions
Keywords
IFIS
Brief summary
Intraoperative Floppy Iris Syndrome (IFIS) may occur during cataract surgeries in patients treated with alpha 1 blockers. IFIS related to alpha 1 blocker Tamsulosin (used for prostate hypertrophy) was reported in 50-90% of patients. IFIS during surgery make the surgery more difficult and raise complication rate. Using anterior corneal incisions was reported briefly in literature as a prophylactic means but was not studied prospectively. we believe (according to our clinical experience) that these anterior incisions do help to reduce the incidence and severity of IFIS signs and complications rate during surgeries.
Interventions
PROCEDUREanterior (more central) corneal paracentesis incision
3 corneal paracentesis incisions will be located 1 mm anterior to the limbus.
Sponsors
Meir Medical Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
55 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. cataract candidates treated (in the present or in the past) with tamsulosin 2. aged 55 or more 3. candidates for topical anesthesia 4. no allergy to anticholinergic or adrenergic drugs 5. able to understand and sign an informed consent
Exclusion criteria
1. history of uveitis 2. iris neovascularization 3. s/p iris surgery 4. traumatic/uveitis induced cataract 5. dialysis / abscence of zonules
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the number of IFIS cases observed during operation. | during the operations |
Secondary
| Measure | Time frame |
|---|---|
| assessing the clinical grade of observed IFIS cases | during the operations |
Countries
Israel
Outcome results
None listed