Brain Dead
Conditions
Keywords
Brain death, CT angiography, Ultrasonography, doppler, transcranial
Brief summary
In France the diagnosis of brain death relies on electroencephalography (EEG) or cerebral angiography. Concerning the latter a time of 6 hours is mandatory between the clinical diagnosis and the realization of the cerebral computed tomography (CT) angiography. Transcranial doppler (TCD) is not recommended in the french guidelines for the diagnosis of brain death. In other countries, some flow patterns allow to confirm the diagnosis of brain death. The hypothesis of our study is that TCD could shorten the time between the clinical diagnosis of brain death and the realization of the CT angiography.
Interventions
OTHERTranscranial doppler
A TCD is performed on all cerebral arteries (mean cerebral arteries, anterior cerebral arteries, basilar trunk, vertebral arteries and carotid arteries) until a flow pattern compatible with brain death is found
Sponsors
Institut d'Anesthesiologie des Alpes Maritimes
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* brain death patients
Exclusion criteria
* craniectomy * post anoxia encephalopathy * no TCD performed before the clinical diagnosis of brain death * transtemporal approach impossible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time between clinical diagnosis of brain death and realization of CT angiography | the outcome is assessed when the CT angiography is performed |
Secondary
| Measure | Time frame |
|---|---|
| Number of CT angiography required for the diagnosis of brain death | the outcome is measured until the diagnosis of brain death is confirmed |
Countries
France
Outcome results
None listed