Dynamic and Static Autoregulation After Brain Injury

Serial Measurement of Static and Dynamic Cerebrovascular Autoregulation After Brain Injury

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01069250

Enrollment

Registered

2010-02-17

Start date

2001-08-31

Completion date

2010-02-28

Last updated

2013-08-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Brain Injuries, Intracranial Hemorrhages, TBI (Traumatic Brain Injury)

Keywords

dynamic cerebrovascular autoregulation, static cerebrovascular autoregulation, acute brain injury, transcranial Doppler ultrasound, critical care

Brief summary

The aim of the study assesses static and dynamic cerebrovascular autoregulation daily over one week in patients with traumatic brain injury or intracranial hemorrhage to quantify the temporal profile of the autoregulatory status.

Interventions

OTHERThere are no interventions in this study

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Traumatic brain injury * Intracranial hemorrhage

Exclusion criteria

* Measurement of TCD were impossible * Injury of the legs (if the both tigh cuffs for dynamic autoregulation could not be fixed)

Design outcomes

Primary

Measure	Time frame
Disturbed cerebrovascular autoregulation after brain injury	7 days

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026