The Effect of Tranexamic Acid on Postoperative Blood Loss and Coagulation in Patients With Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; Double Blind Randomized Control Study

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01067638

Enrollment

Registered

2010-02-11

Start date

2009-11-30

Completion date

2010-09-30

Last updated

2010-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Occlusive Disease

Brief summary

The Effect of Tranexamic Acid on Postoperative Blood loss and Coagulation in Patients with Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; double blind randomized control study.

Interventions

DRUGTranexamic Acid

1.0g loading dose before skin incision and continuous infusion 200 mg/h during surgery

Study design

Allocation

RANDOMIZED

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* Fifty patients undergoing OPCAB with preoperative hematocrit levels lower than 35%

Exclusion criteria

Patient who has * Open heart surgery history before * Thrombosis history * Myocardial infarction (MI) within 7days recently * Liver or Kidney disease * been scheduled emergency surgery

Design outcomes

Primary

Measure	Time frame
Tranexamic acid significantly reduce the amount and incidence of homologous transfusion in anemic patients undergoing off-pump coronary artery bypass (OPCAB)	Check the amount 3 times before sugery and 24 hours after surgery

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026