Central Nervous System Tumors
Conditions
Keywords
Proton Radiation, Central Nervous System (CNS) Tumors, Brain, Spine, Cancer, Radiation Therapy (RT)
Brief summary
The purpose of this study is to collect information from medical records to see what effects proton beam radiation has on cancer and analyze possible side effects.
Detailed description
Data collection will be obtained from the patient's medical records including initial evaluation, radiotherapy completion records and follow-up.
Interventions
None listed
Sponsors
University of Florida
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Days to 20 Years
Healthy volunteers
No
Inclusion criteria
* Estimated \>5 cc of the brain tissue to receive \>5 CGE radiation * Patient must be less than 21 years of age at time of consent. * Patients that require localized and craniospinal irradiation. * Patients and/or patient parent must complete baseline Quality of Life Questionnaire as applicable by patient age group.
Exclusion criteria
* Prior radiation therapy. * Evidence of metastases outside the central nervous system.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measure late effects of proton therapy on pediatric patients with CNS tumors | 5.4 years after treatment completion |
Secondary
| Measure | Time frame |
|---|---|
| Survival endpoints of local control, progression-free survival, and overall and cause-specific survival. | 12 years after treatment completion |
Countries
United States
Outcome results
None listed