Swallowing
Conditions
Keywords
anterior, cervical, fusion, swallowing, Swallowing after anterior cervical discectomy and fusion, Bony fusion rates post anterior cervical discectomy and fusion
Brief summary
Anterior cervical discectomy and fusion with or without decompression is a well-established surgical treatment for spine patients with the appropriate indications. Anterior approach involves some retraction that affect the midline structures of the anterior neck. Irritation and swelling may result, leading to postoperative dysphagia and the less common but critically important occurrence of postoperative airway compromise. Steroids given intraoperatively may reduce the incidence of these adverse outcomes by reducing the degree of swelling within the anterior neck subsequent to local surgical tissue trauma. The investigators hypothesize that the use of steroids intraoperatively provides a significant benefit to the patient, in terms of reduced incidence of dysphagia and airway compromise.
Interventions
Decadron will be given at a dose of 0.2 mg/kg intraoperatively, followed by Decadron 4 mg. every 6 hours for 24 hours.
Placebo saline will be given intraoperatively as well as 4 doses every 6 hours for 24 hours.
Sponsors
Study design
Eligibility
Inclusion criteria
* 18 years of age or greater * Cervical spondylosis requiring surgical treatment at 2 or more motion segments * Ventrally - approachable vertebral levels
Exclusion criteria
* Minors (under 18 years old) * Pregnant women * Patients currently taking steroids * Patients requiring surgical treatment at only one segment * Comatose or incapacitated patients who cannot consent to participate * Wards of the state * Persons with an allergy to dexamethasone or related drugs * Persons employed at Albany Medical Center
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| subjects will demonstrate good bony fusion | one year |
Countries
United States