Study on Hemodialysis: Illumination Effects

Effects of Light Therapy on Sleep, Melatonin Rhythm and Mood in Hemodialysis Patients

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01064544

Acronym

SHINE

Enrollment

Registered

2010-02-08

Start date

2010-03-31

Completion date

2010-09-30

Last updated

2011-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep Problems

Keywords

Sleep problems, melatonin, mood, Hemodialysis

Brief summary

Previous research has shown that sleep quality in hemodialysis patients is disturbed. One of the possible explanations is an insufficient or disturbed melatonin rhythm. Melatonin rhythm is regulated by exposure to light. In this feasibility study, the investigators examine the effects of light therapy during dialysis on sleep, melatonin rhythm and mood.

Interventions

PROCEDURElight therapy with the device: EnergyLight

2 hr of light therapy during each hemodialysis session

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* informed consent * men/women aged 18-85 years * knowledge of the dutch language * hemodialysis patient * subjective sleep problems (Epworth sleepiness score \>9)

Exclusion criteria

* known major illness, which interferes with patient's participation * use of melatonin/hypnotics * use of photosensitizing medication * jet lag or travel \> 1 time zone

Design outcomes

Primary

Measure	Time frame
Improvement of sleep parameters	3 weeks

Secondary

Measure	Time frame
Change in subjective sleep parameters	3 weeks
Change in mood	3 weeks
change in melatonin concentrations	3 weeks

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026