Supratentorial Brain Tumor
Conditions
Keywords
bispectral index, lesions, consciousness
Brief summary
The purpose of this study is to assess whether BIS values at return of consciousness are different in patients with or without brain tumors.
Interventions
DEVICEBIS values at return of consciousness in patients + predicted and measured propofol plasma concentrations
Difference between left- and rightsided BIS values in patients with supratentorial brain tumor during course and Comparison between predicted and measured propofol plasma concentrations during course of the study
Sponsors
University Medical Center Groningen
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients undergoing elective craniotomy for removal of frontal or frontotemporal brain tumors. * Control group: Neurosurgical patients without intracranial pathology.
Exclusion criteria
* Patient refusal * Significantly increased intracranial pressure * Uncontrolled arterial hypertension * Significant coronary artery disease * Anticipated difficult airway * Decreased level of consciousness * Existing motor weakness dominant arm/hand * Impaired hearing * Nausea, vomiting
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bilateral BIS values at return of consciousness in patients with and without supratentorial brain tumor. | one year |
Secondary
| Measure | Time frame |
|---|---|
| Difference between left- and rightsided BIS values in patients with supratentorial brain tumor during course and Comparison between predicted and measured propofol plasma concentrations during course of the study | one year |
Countries
Netherlands
Outcome results
None listed