Altered Faecal Protease Activity in Irritable Bowel Syndrome Patients in China

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01060527

Enrollment

Registered

2010-02-02

Start date

2010-01-31

Completion date

Unknown

Last updated

2010-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irritable Bowel Syndrome

Keywords

irritable bowel syndrome,protease activity,China

Brief summary

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder haracterised by abdominal pain or discomfort associated with altered bowel habits,while the mechanism is still not understood.Recent advances have conceptualized the faecal supernatants of diarrhoea-predominant IBS have a substantially higher serine protease activity, while in china,almost no studies have reported about protease activity in IBS.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients fulfilling the Rome III criteria for IBS participated in the study -

Exclusion criteria

* Organic gastrointestinal disorders were excluded by detailed blood and stool analyses, serological assays and colonoscopy.

Outcome results