Bioavailability of Nutrients Contained in Softgel Capsules vs Tablets

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01057966

Enrollment

Registered

2010-01-28

Start date

2010-02-28

Completion date

2011-09-30

Last updated

2012-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vision

Keywords

Bioavailability, Ocular Vitamins

Brief summary

This study is a comparison of the bioavailability of nutrients contained in softgel capsules vs tablets.

Interventions

DIETARY_SUPPLEMENTICAPS Eye Vitamin and Mineral Supplement - Softgel (full strength)

Single full strength dose capsule taken one time

DIETARY_SUPPLEMENTICAPS Eye Vitamin and Mineral Supplement - Softgel (half strength)

Single half strength dose capsule taken one time

DIETARY_SUPPLEMENTICAPS Eye Vitamin and Mineral Supplement - Coated Tablets (full strength)

Single, full strength dose tablet taken one time

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

1. Age 18 to 35 2. Body Mass Index (BMI) 21-27 kg/m2 3. Must be able to give written informed consent 4. Subjects must be willing to comply with all study requirements. 5. Subjects must understand, sign and be given a copy of the written Informed Consent form.

Exclusion criteria

1. Subjects for whom both eyes do not meet all inclusion criteria and either eye meets

Design outcomes

Primary

Measure	Time frame
Bioavailability of nutrients	1 week for each treatment cross-over period

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026