Effects of Nutritional Supplementation and Dietary Advice in Elderly Patients After Hospital Discharge.

Effects of Six Months Treatment With Nutritional Supplements or Dietary Advice, Alone or in Combination on Mortality, Health-related Quality of Life and Health-care Consumption for Elderly Patients at Risk of Malnutrition.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01057914

Enrollment

671

Registered

2010-01-28

Start date

2010-02-28

Completion date

2020-11-30

Last updated

2020-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnutrition

Keywords

Randomized controlled trial, Malnutrition, Aged, Aged 80 and over, Nutrition therapy

Brief summary

The purpose of this study is to evaluate the effects of nutritional therapy in elderly malnourished patients. The hypothesises are that nutritional supplementation and dietary advice alone or in combination affects mortality, quality of life and health-care consumption after six month of treatment.

Interventions

DIETARY_SUPPLEMENTNutritional supplementation with a liquid formula

The patient consumes 400 kcal from a liquid supplementation formula

OTHERDietary advice

The patient receives dietary advice for one hour during the hospital stay.

OTHERCombination of supplement and dietary advice

The patient receives dietary advice for one hour during the hospital stay and consumes 400 kcal from liquid supplementation formula for six month after discharge.

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* ≥65 years old * Admitted to one of the participating wards during the recruitment period

Exclusion criteria

* Well-nourished * No consent to participate * Not able to communicate * Not able to understand swedish * Presumed life-expectancy \<1 year * Already receiving nutritional therapy including dietary advice, supplements, tube-feeding or parenteral nutrition * Dietary restrictions due to illness or disease inconsistent with the intervention * Impaired cognitive function or dementia * Body mass index ≥35 * Living in old peoples homes, sheltered housing, institution, service flats or nursing homes * Participant in a study evaluating differences in 3-year mortality between well-nourished patients, patients at risk of malnutrition and malnourished patients

Design outcomes

Primary

Measure	Time frame
All cause mortality	Six months, one year, three years

Secondary

Measure	Time frame
Health-related quality of life	Six months, one year, three years
Health-care consumption	Six months, one year, three years
Function in activities in daily life	Six months, one year, three years

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 18, 2026