Effects of Caffeine on Methacholine Challenge and Exhaled Nitric Oxide Levels.

The Effects of Caffeine on Exhaled Nitric Oxide Levels and Methacholine PC20

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01057875

Enrollment

Registered

2010-01-27

Start date

2010-01-31

Completion date

2010-02-28

Last updated

2010-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma

Brief summary

To investigate whether or not the ingestion of caffeine with alter airway responsiveness to methacholine and/or change the level of exhaled nitric oxide.

Interventions

OTHERcaffeine

Starbuck's Grande Pike Roast coffee

OTHERNo caffeine

Starbuck's Grande Pike Roast Decaffeinated Coffee

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* clinical diagnosis of asthma * FEV1 greater than 65%

Exclusion criteria

* asthma is poorly controlled * presence of other airway disease (e.g. COPD)

Design outcomes

Primary

Measure	Time frame
methacholine pc20	1 hour post ingestion

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 28, 2026