Chronic Obstructive Pulmonary Disease
Conditions
Keywords
COPD, inspiratory muscles, diaphragm
Brief summary
Uncertainty persists regarding the usefulness of incorporating inspiratory muscle training (IMT) in pulmonary rehabilitation programs for patients with chronic obstructive pulmonary disease. In this study the investigators investigate whether IMT associated with exercise training would be better than exercise training alone, with regard to exercise capacity, inspiratory muscle strength and dyspnea.
Detailed description
Study design: A double-blind parallel controlled trial Setting: outpatient clinic Inclusion criteria: Subjects between 40 and 75 years of age referred by a physician to the Pulmonary Rehabilitation Program, with a clinical and spirometric diagnosis of moderate to severe COPD according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD). Outcome measurements: Inspiratory muscle strength (using maximal inspiratory pressure, MIP), exercise capacity (using six-minute walk test) and dyspnea were measured.
Interventions
OTHERInspiratory muscle training
The training was performed using a threshold inspiratory muscle trainer (Respironics HealthScan, Inc, Cedar Grove, New York, USA). The patients performed the IMT training in a seated position, with the upper limbs supported. The total duration of the respiratory training was 30 minutes, with sequences of three minutes of training followed by pauses of two minutes. The initial load was equivalent to 30% of the individual's MIP. This load was progressively increased over the first four weeks, according to the patients' tolerance, to reach 60% of the MIP. This level was then maintained until the end of the training.
Sponsors
Faculdade Evangelica do Parana
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Subjects with a clinical and spirometric diagnosis of moderate to severe COPD according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) * In a stable condition (without exacerbations or infections for at least a month) * Had to be former smokers (\> 6 months without smoking) * subjects referred by a physician to the Pulmonary Rehabilitation Program
Exclusion criteria
* Subjects with a known history of asthma, or severe and/or unstable heart disease or any other pathological condition that could impair their physical activities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inspiratory muscle strength | 8 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Exercise capacity | 8 weeks |
| Dyspnea | 8 weeks |
Outcome results
None listed