Diagnostic of Infections Following Major Abdominal Surgery and Burn Injury

Impact of Biomarkers for Early Diagnostic of Infections Following Major Abdominal Surgery and Severe Burn Injuries

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01055587

Acronym

Earlygnost

Enrollment

120

Registered

2010-01-25

Start date

2009-09-30

Completion date

2015-06-30

Last updated

2017-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Second Degree Burn, Third Degree Burn

Keywords

major abdominal surgery, severe burn injury, infection, diagnostic

Brief summary

This study was designed to investigate, if new biomarkers may improve the early diagnostic of infections following major abdominal surgery and severe burn injuries.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients with major abdominal surgery (e.g. gastrectomy, hemi-/colectomy, resection of sigma or rectum, resection of liver, esophagectomy) * patients following severe burn injury (burn surface area \>= 15%) * age \>= 18 years * informed consent

Exclusion criteria

* no informed consent * emergency surgery * immunocompromising diseases (e.g. HIV+, AIDS, Lymphoma or NonHodgkin-Lymphoma, Autoimmune-Diseases) * pre-existing liver or renal failure * chronic therapy with corticoids

Design outcomes

Primary

Measure	Time frame
rate of infections	day 28 post intervention

Countries

Germany

Outcome results