Osteoarthritis of Knee Joint
Conditions
Brief summary
The purpose of this study was to compare the pain relieving action of the lornoxicam and diclofenac in patients of OA knee.
Interventions
DRUGDiclofenac
Tab. Diclofenac 50 mg 12 hrly, orally, in morning and in evening after taking food for 3 months.
DRUGLornoxicam
Tab. Lornoxicam 4 mg , orally, 8 hourly after taking food in morning , in noon and evening for 3 months.
Sponsors
Government Medical College, Bhavnagar
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
25 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Newly diagnosed patient aged between 25 to 65 yrs of either gender suffering from osteoarthritis of knee according to criteria given by American College of Rheumatology * Informed consent obtained from the patient.
Exclusion criteria
* Patients with any other systemic llness, * Patients with pregnancy and lactation, * Patients taking other drugs like lithium\[4\], digoxin, methotrexate, anticoagulants, antidiabetics, diuretics, * Patients with H/O hypersensitivity to NSAIDs, * Patients who had consumed any analgesics in last 1 month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in reduction in reading of Wong Baker face pain scale and in time of 100 meters walking test | 3 months |
Secondary
| Measure | Time frame |
|---|---|
| To monitor side effects of study drugs. | 3 months |
Countries
India
Outcome results
None listed