Transversus Abdominus Plane Block

Ultrasound Guided Transversus Abdominus Plane Block for Patients Undergoing Laparoscopic Hand-assisted Nephrectomy.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01054469

Enrollment

Registered

2010-01-22

Start date

2010-03-31

Completion date

2012-02-29

Last updated

2012-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nephrectomy

Keywords

nephrectomy

Brief summary

Transversus Abdominus Plane (TAP) block may reduce need for postoperative pain medications in patients undergoing laparoscopic hand assisted nephrectomy. Our hypothesis is that the TAP block will result in a significant reduction in pain scores and morphine requirements in the active group.

Interventions

PROCEDURETAP block placement with placebo

20 ml of normal saline (placebo)

PROCEDUREPlacement of block with ropivacaine

20 ml of 0.5% ropivacaine hydrochloride

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Patients who are ≥ 18 and ≤ 80 years of age. * Patients scheduled to undergo hand assisted laparoscopic removal of a single kidney for either tumor or living donor transplantation.

Exclusion criteria

* Patients scheduled to undergo an open procedure for nephrectomy * Patients who are converted from hand assisted laparoscopic surgery to open surgery due to intraoperative complications. * Bilateral nephrectomy * Pregnant or lactating patients * Patients unable or unwilling to provide informed consent * Patients unable to comprehend the use of a visual analog scale * Patients desiring preemptive antiemetics * Opioid tolerance * Allergy to amide local anesthetics or any of the study drugs (morphine). * Contraindication to regional nerve block (bleeding disorder, infection at site of block) * Patients with history of dementia

Design outcomes

Primary

Measure	Time frame
Determine if TAP block is a viable alternative to PCA narcotics for the control of pain after hand-assisted, laparoscopic nephrectomy.	24 hours postoperatively

Secondary

Measure	Time frame
TAP block with ropivacaine will lead to equivalent or better results with regard to the following outcomes:pain scores, nausea, vomiting, sedation, request for PCA, discontinuation of Foley catheter, discharge from the hospital	24 hours postoperatively

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026