Propofol Versus Midazolam With Fentanyl for EGD Endomicroscopy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01053871

Enrollment

104

Registered

2010-01-22

Start date

2010-01-31

Completion date

2010-05-31

Last updated

2011-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional Dyspepsia, Gastritis

Keywords

normal

Brief summary

This trial aims to compare the endomicroscopic image quality and sedation efficacy of propofol or midazolam with fentanyl.

Interventions

DRUGpropofol

conscious sedation using propofol

DRUGmidazolam with fentanyl

conscious sedation using midazolam with fentanyl

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* outpatients attending endomicroscopy * able to give written informed consent

Exclusion criteria

* GI tract malignancy * coagulopathy * acute upper digestive tract bleeding * pregnancy or breast feeding * allergy to fluorescein sodium * impaired renal function

Design outcomes

Primary

Measure	Time frame
endomicroscopic image quality	3 months

Secondary

Measure	Time frame
sedation efficacy outcomes,patient assessment,physician assessment	3 months

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026