Diabetes, Insulin Resistance
Conditions
Keywords
Glycemic index, Anthocyanin, Potato, Polyphenol
Brief summary
The purpose of this study is to determine the glycemic index of four varieties of potatoes and to determine the bioavailability of polyphenols contained in these potatoes.
Detailed description
Ten healthy persons will have a fasting blood sample drawn and asked to randomly consume a 50g glucose drink (2 occasions), or 50g carbohydrate equivalent of cooked purple, red, yellow and white potatoes. Further blood samples will be obtained at 15,30, 45, 60, 90, 120, 180, 240 mins. Bloods from the first 2 hours will be analyzed for glucose and insulin to determine the glycemic response. Hourly blood samples will be analyzed for polyphenol to determine the bioavailability of polyphenols from the different potato variety. Urine samples will be collected before ingestion of the food items and again at 4 hours, and will be used to determine polyphenol bioavailability.
Interventions
OTHERGlycemic response to different varieties of potatoes
the glycemic response top 50g available carbohydrates from 4 potato varieties will be compared to a 50g glucose standard
Sponsors
Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Guelph Food Research Centre
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy, non-smoker on no medication * normal glucose tolerance * willing to have a catheter inserted in forearm
Exclusion criteria
* abnormal glucose tolerance * abnormal BMI * on medication for a chronic disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycemic response | 2 hrs |
Secondary
| Measure | Time frame |
|---|---|
| Bioavailability of polyphenols from potatoes | 4 hours |
Countries
Canada
Outcome results
None listed