Obstructive Sleep Apnea and Venous Thromboembolism

Patients With Obstructive Sleep Apnea (OSA), Independent of Obesity, Are at Increased Risk of Venous Thromboembolic Events (VTE)

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01051297

Acronym

OSAVTE

Enrollment

Registered

2010-01-18

Start date

2009-03-31

Completion date

2015-05-31

Last updated

2016-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive Sleep Apnea, Pulmonary Embolism, Venous Thromboembolism, Venous Thrombosis

Keywords

Obstructive sleep apnea, venous thrombosis, pulmonary embolism, venous thromboembolism

Brief summary

There is a clear link between obstructive sleep apnea (OSA) and cardiovascular disease. However, there has been no clear link between OSA and venous thromboembolism (VTE). The objective of this study is to evaluate such a link.

Detailed description

Design: 1. retrospective chart review of all patients with VTE over 10 year period 2. retrospective chart review of all patients with OSA over 10 year period 3. prospective 1 year follow up of all patients diagnosed with new VTE 4. prospective 1 year follow up of all patients undergoing sleep study

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult patients (\>= 18 years) with sleep study, OSA or VTE

Exclusion criteria

* Below 18 years of age

Design outcomes

Primary

Measure	Time frame
incidence of VTE for the OSA cohort	12 months
incidence of OSA for the VTE cohort	12 months

Secondary

Measure	Time frame
death	12 month
bleeding	12 months
composite outcome of death, VTE , or bleeding	12 months

Outcome results