Erectile Dysfunction, Type 2 Diabetic Patients
Conditions
Keywords
type 2 diabetes mellitus, male, erectile dysfunction
Brief summary
The investigators evaluated 250 male, type 2 diabetic patients, aged 18-80 years. They will undergo IIEF (International Index of Erectile Function), SAS of Zung (self-rating anxiety state)and SDS of Zung (self-rating depression scale)questionnaires. The investigators will evaluate anthropometric and biochemical parameters, dysautonomic function index, IMT (Intima Media Thickness) index, and fundus oculi examen. Furthermore, the investigators will perform MNSI (Michigan Neuropathy Screening Instrument) and NDS (Neuropathy Disability Score)questionnaires.
Interventions
OTHERtype 2 diabetic patients
males; type 2 diabetic patients
Sponsors
University of Pavia
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
MALE
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* type 2 diabetes mellitus
Exclusion criteria
* type 1 diabetes mellitus * \< 18 years old * anatomic abnormalities of the penis * patients taking erectile dysfunction therapy at the moment of the enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of erectile dysfunction | Baseline (time 0); 3 months; 6 months |
| Description of erectile disfunction markers | Baseline (time 0); 3 months; 6 months |
| Evaluation of diabetic neuropathy in patients with erectile dysfunction | Baseline (time 0); 3 months; 6 months |
Secondary
| Measure | Time frame |
|---|---|
| Metalloproteinases 2 and 9 | Baseline (time 0); 3 months; 6 months |
| Insulin-sensitivity index (HOMA index) | Baseline (time 0); 3 months; 6 months |
| Glycemic control | Baseline (time 0); 3 months; 6 months |
Countries
Italy
Outcome results
None listed