Diabetes, End Stage Renal Disease
Conditions
Keywords
Diabetes mellitus, ESRD, CGM, Inflammation markers, Hemodialysis, Diabetic patients, Nondiabetic patients, All with ESRD, All undergone hemodialysis
Brief summary
Evaluation of different glycemic variations between the dialysis period and non-dialysis period in two groups: nondiabetic and diabetic patients undergone two different hemodialysis methods. Thirty-six patients, males and females, aged 50-80 years, with end stage renal disease (ESRD) will undergo hemodialysis and continuous glucose monitoring (CGM). The investigators will evaluate also inflammation markers before and after the different hemodialysis methods.
Interventions
DEVICEContinuous Glucose Monitoring (CGM)
CGM allocated one time for 3 days
Sponsors
University of Pavia
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
50 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* patients with or without diabetes mellitus * ESRD * undergone hemodialysis * males and females aged 50-80
Exclusion criteria
* tumors * chronic inflammation diseases * AMI * acute pulmonary diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -Hemodialysis tolerability -Hypoglycemia numbers -Hyperglycemia numbers -Inflammation markers | before and after each procedure |
Secondary
| Measure | Time frame |
|---|---|
| variations of glycemia during the night; insulin-sensitivity | at the beginning of the first hemodialysis and at the end of the second hemodialysis |
Countries
Italy
Outcome results
None listed