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Blue Enriched Versus Standard Light Treatment for Seasonal Affective Disorder(SAD)

Gerandomiseerde en Gecontroleerde Studie Naar de Effecten Van Lichttoediening Met Een Hogere Kleurtemperatuur in Vergelijking Met de Standaard Lichttherapie in de Behandeling Van Winterdepressie

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01048294
Enrollment
52
Registered
2010-01-13
Start date
2005-10-31
Completion date
2006-03-31
Last updated
2010-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seasonal Affective Disorder

Keywords

Seasonal affective disorder, phototherapy, circadian rhythms, blue enriched light, melanopsin, Primary disease: Seasonal Affective Disorder, winter type

Brief summary

One of the most frequently investigated hypothesis of the pathophysiology underlying Seasonal Affective Disorder(SAD) or so called winterdepression is a disturbance of circadian rhythms. Since the circadian system is especially sensitive for the blue portion of the light spectrum, a new light therapy device with more blue light (blue enriched polychromatic light) was tested for its efficacy to treat SAD. In chronobiological terms this light is hypothesized to be more potent in inducing non-visual effects. In the present study fluorescent tubes that emit a high portion of short wavelength light on top of the normal wavelengths are tested for its superiority in treating SAD. This blue-enriched light (colour temperature 17000 ºK) is compared to standard light treatment (5000 º K) in SAD patients., The investigators hypothesise that blue- enriched light improve the therapeutic effects of light treatment leading to a higher response or the same response in a shorter time schedule compared to standard light treatment.

Interventions

DEVICEOriginal Energy Light,

9000 lux, 30 minutes in the morning

DEVICEOriginal Energy Light prototype

9000 lux 20 minutes in the morning

Sponsors

University Medical Center Groningen
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* age 18-65; * diagnosis of Seasonal affective Disorder, winter type according to DSM-IV; * SIGH SAD rating higher then or equal to 18 on day 1; * no other treatments for mood disorder during the study * stay in the Netherlands during the study

Exclusion criteria

* other Axis 1 disorder according to DSM-IV * acute suicide risk * use of psychotropic drugs or photosensitizing drugs * eye diseases other then usual effect of aging * diabetes or epilepsy * regular shift work

Design outcomes

Primary

MeasureTime frame
SIGH SAD depression observer ratingdays 1, 8, 15, 22

Secondary

MeasureTime frame
selfrating of depressive moodonce daily during 22 days

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 28, 2026