Genomic Analysis of Pediatric Bone Tumors

Genomic Analysis of Pediatric Bone Tumors (Other Title: Pediatric Bone Tumor Biology Study)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01047878

Enrollment

163

Registered

2010-01-13

Start date

2007-08-31

Completion date

2019-12-31

Last updated

2020-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Cancer

Brief summary

To determine whether gene expression analysis of primary tumor samples before and after chemotherapy are predictive of long-term survival in pediatric patients with bone sarcomas (Ewings sarcoma (ES) and Osteosarcoma(OS)).

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 18 Years

Healthy volunteers

Inclusion criteria

All patients with bone x-rays suggestive of a malignant bone tumor

Exclusion criteria

Patients with a known diagnosis of cancer.

Design outcomes

Primary

Measure	Time frame
% necrosis post chemotherapy	his is measured at the time of sample collection since we are looking for % necrosis in the sample we are collecting
overall survival and event free survival	This is measured at the time the patient dies, or at the time when patient relapses from their disease. There is no set time since this outcome is individually assessed.

Countries

United States

Outcome results