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Effect of Air-stacking on Peak Cough Flow in Patients With Acute Cervical or High Thoracic Spinal Cord Injury

Effect of Two Different Air-stacking Techniques, Combined With Manually Assisted Cough, on Peak Cough Flow (PCF) in Patients With Acute Cervical or High Thoracic Spinal Cord Injury

Status
Withdrawn
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01046175
Enrollment
10
Registered
2010-01-11
Start date
2010-02-28
Completion date
2011-06-30
Last updated
2010-11-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Cord Injury, Tetraplegia

Keywords

Respiratory complications, respiratory insufficiency, respiratory therapy

Brief summary

Respiratory complications continue to be one of the leading causes of morbidity and mortality in people with spinal cord injury, especially among cervical and higher thoracic injuries. Both inspiratory and expiratory function are often severely decreased, leading to respiratory complications, such as atelectasis, pneumonia and ventilatory failure. The prevention of these respiratory complications needs to begin immediately after injury. To achieve effective expelling of secretions before they form mucus plugs, it is essential to improve patients ability to cough. Manually assisting the cough is one way of increasing cough flow, but an effective cough also requires adequate lung volumes. The emphasis should therefore be on expansion of the lungs before coughing. One way of expanding the lungs is by air-stacking. In air-stacking insufflations are stacked in the lungs to maximally expand them. Cough can be valued by measuring Peak Cough Flow (PCF). By combining air-stacking with manually assisted cough the PCF can be increased sufficiently. The aim of this study is to compare the effect of two different air-stacking techniques on PCF, air-stacking on a respirator versus air-stacking with a manual resuscitator.

Interventions

PROCEDUREAir-stacking with a manual resuscitator

Stacking air into the lungs up to maximal insufflation capacity (MIC)with a manual resuscitator

PROCEDUREAir-stacking with ventilator

Stacking air into the lungs to maximal insufflation capacity (MIC) with ventilator

Sponsors

Ullevaal University Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* acute cervical or high thoracic spinal cord injury admitted to the ICU

Exclusion criteria

* substantial abdominal or thoracic injury * substantial brain damage * intubated or tracheostomized patients * not able to cooperate * pregnant women

Design outcomes

Primary

MeasureTime frame
Peak cough flow (PCF)2 weeks

Secondary

MeasureTime frame
Patient preference of air-stacking technique2 weeks
Physiotherapist preference of air-stacking technique2 weeks

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026