Early Ambulation
Conditions
Brief summary
The aim is to replicate, develop, and pilot test a model of care for the prevention and management of functional decline of older patients during hospitalization.
Detailed description
to develop an intervention protocol that achieves clinical development objectives in a scientifically rigorous and time efficient manner.
Interventions
BEHAVIORALa modified NTU-HELP
The intervention consists of a daily inpatient care protocol on three core intervention protocols on top of hospital routine care.
Sponsors
National Health Research Institutes, Taiwan
National Science and Technology Council, Taiwan
National Taiwan University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age 65 year and older * Length of Stay is over 6 days * Able to communicate verbally or in writing
Exclusion criteria
* Coma * Mechanism ventilation * Aphasia, if communication ability is severely impaired * Terminal condition with comfort care only, death imminent * Combative or dangerous behavior * Severe psychotic disorder that prevents patient from participating in interventions * Severe dementia (e.g. unable to communicate; MMSE=0). For patients with severe impairment (e.g. MMSE\<10), decision to enroll will be made on a case-by-case basis depending on their ability to participate in intervention. * Respiratory isolation (e.g. tuberculosis). Patients on contact isolation (e.g. vancomycin-resistant enterococcus) or droplet precautions will be enrolled. * Discharge firmly anticipated within 6 days of admission. Enroll if discharge date unsure * Refusal by patient or family member. * Others. Reason to be well documented.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative bowel dysmotility | through study completion, an average of 3 months | Record the incidence of postoperative bowel dysmotility developing during hospitalization after surgery |
| Functional status:Barthel Index. | through study completion, an average of 3 months | Changes from Baseline Barthel Index (BI) scores at 6 weeks after discharge |
| Mini-Nutritional Assessment scores (MNA) | through study completion, an average of 3 months | Changes from Baseline Mini-Nutritional Assessment (MNA) scores at 6 weeks after discharge |
| Mini Mental State Examination scores (MMSE) | through study completion, an average of 3 months | Changes from Baseline Mini Mental State Examination (MMSE) scores at 6 weeks after discharge |
| Frailty rates and transition between frailty states | through study completion, an average of 3 months | Changes from Baseline Frailty rates at 6 weeks after discharge |
| Postoperative delirium incidence rate [Confusion Assessment Method (CAM)] | through study completion, an average of 3 months | Record the incidence of postoperative delirium developing during hospitalization after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Body weight | through study completion, an average of 3 months | Changes from Baseline Body weight at 6 weeks after discharge |
| Grip strength | through study completion, an average of 3 months | Changes from Baseline Grip strength at 6 weeks after discharge |
| Oral health | through study completion, an average of 3 months | i.e., plaque index, screens of swallowing function |
| Executive function | through study completion, an average of 3 months | ie.e, color trail test |
| Geriatric Depressive Scale scores (GDS) | through study completion, an average of 3 months | Changes from Baseline Geriatric Depressive Scale scores (GDS) at 6 weeks after discharge |
| Length of Hospital Stay (LOS) | through study completion, an average of 3 months | Record the length of hospital stay for abdominal surgery |
Countries
Taiwan
Outcome results
None listed