Measurement of Colloid Osmotic Pressure in Plasma and Interstitial Fluid in Children

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01044641

Enrollment

Registered

2010-01-08

Start date

2009-12-31

Completion date

2013-05-31

Last updated

2014-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colloid Osmotic Pressure

Keywords

Colloid Osmotic pressure in interstitial fluid, Colloid Osmotic pressure in plasma, Protein fractions in interstitial fluid

Brief summary

The purpose of this study is to identify normal values of colloid osmotic pressure in interstitial fluid and plasma in healthy children between 2 and 10 years.

Detailed description

Measurements of colloid osmotic pressure (COP) by sampling of interstitial fluid from subcutaneous tissue and plasma are well documented in animal models and human adult studies. COP plays a major role in transcapillary fluid balance and is valuable in fluid therapy planning in critically ill patients. There are no data regarding interstitial fluid COP values in neither sick nor healthy children. Sampling of interstitial fluid by the wick method in children who is under general anaesthesia (ear-nose-throat operations) gives the opportunity to identify normal COP values in this age group.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

2 Years to 10 Years

Healthy volunteers

Yes

Inclusion criteria

* Children from 2 to 10 years

Exclusion criteria

* Medication * Ongoing illness * Syndromes

Design outcomes

Primary

Measure	Time frame
Colloid osmotic pressure	60 minuttes after wick insertion

Countries

Norway

Outcome results