Correlation of Albuminuria With Arterial Stiffness

Assessment of the Association Between Albuminuria and Arterial Stiffness in Diabetic Patients, Hypertensive Patients and Healthy Controls

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01041599

Enrollment

152

Registered

2010-01-01

Start date

2009-10-31

Completion date

2012-02-29

Last updated

2016-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Albuminuria, Diabetes Mellitus, Hypertension, Vascular Stiffness

Keywords

Diabetes Mellitus, Hypertension, Albuminuria, vascular stiffness

Brief summary

The investigators aim to investigate the relationship between albuminuria and arterial stiffness in diabetic patients, hypertensive patients and healthy subjects.

Detailed description

CONTEXT: Albuminuria is an important cardiovascular risk factor. Arterial stiffness also gives important information about atherosclerosis. Oscillometric methods may be useful in assessing arterial stiffness in a mainly operator independent way. OBJECTIVE: We aim to investigate the relationship between albuminuria and arterial stiffness measured with an oscillometric device in diabetic patients, hypertensive patients and healthy subjects. METHODS: 152 diabetic patients, 152 hypertensive patients and 152 healthy subjects are planned to be enrolled in this study. The measurements will be done between 9:00 and 13:00. After the measurements, blood and urine samples will be obtained, centrifugated and kept in -80°C until assayed. Afterwards, echocardiographic left ventricle mass index will be calculated. The correlation between albuminuria and arterial stiffness will be assessed as the primary outcome measure.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Yes

Inclusion criteria

* Diabetes Mellitus * Hypertension * Healthy subjects

Exclusion criteria

* Symptomatic cardiovascular diseases (heart failure, history of myocardial infarction, etc.) * Renal failure * Pregnancy * Diseases of the aorta

Design outcomes

Primary

Measure	Time frame
Correlation between albuminuria and arterial stiffness	Albuminuria and arterial stiffness will be assessed simultaneously (i.e. in the same morning)

Countries

Turkey (Türkiye)

Outcome results